Article last updated: October 15, 2024
Tetrapeptide-40, also known as a synthetic peptide consisting of alanine, asparagine, and threonine, is a relatively recent addition to the world of cosmetic ingredients. In the realm of skincare, peptides are short chains of amino acids that serve as the building blocks of proteins like collagen and elastin, which are crucial for maintaining the skin’s structure and elasticity. Tetrapeptide-40 is specifically engineered in laboratories, making it a synthetic compound rather than one derived from natural sources.
The journey of Tetrapeptide-40 into cosmetic formulations began with advancements in peptide synthesis technology. Scientists discovered that by combining specific amino acids in precise sequences, they could create peptides with targeted skin benefits. Tetrapeptide-40 emerged from this research as a promising ingredient for skin conditioning, which is its primary function according to the CosIng Database.
The production of Tetrapeptide-40 involves a process called solid-phase peptide synthesis (SPPS). This method allows for the sequential addition of amino acids to a growing peptide chain, ensuring high purity and consistency. Each amino acid is carefully bonded to the next, forming the tetrapeptide structure. Once the synthesis is complete, the peptide is purified and tested for quality before being incorporated into cosmetic products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Tetrapeptide-40:
Tetrapeptide-40 is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition. When included in cosmetic formulations, Tetrapeptide-40 can help improve the overall appearance and feel of the skin. It works by enhancing the skin’s natural barrier function, which can lead to a smoother, more hydrated complexion. Essentially, it helps your skin look and feel healthier by supporting its natural functions.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Tetrapeptide-40 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Tetrapeptide-40 during pregnancy and breastfeeding are lacking. Therefore, it is advisable to consult a healthcare professional for further advice.
Side effects and adverse reactions from Tetrapeptide-40 are generally uncommon. However, it is recommended to conduct a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, Tetrapeptide-40 is rated as 0 on a scale of 0 to 5, meaning it is considered non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
