Article last updated: October 15, 2024
Tetrapeptide-17 is a synthetic peptide that has garnered attention in the cosmetic industry for its skin conditioning properties. Chemically, it is composed of a sequence of amino acids: arginine, lysine, and phenylalanine. These amino acids are the building blocks of proteins, and when combined in this specific sequence, they form a tetrapeptide known for its potential benefits to the skin.
The journey of Tetrapeptide-17 into the realm of cosmetics is relatively recent. Initially developed through advanced peptide synthesis techniques, it was designed to mimic naturally occurring peptides in the skin that play a role in maintaining its structure and function. The synthetic nature of Tetrapeptide-17 allows for greater stability and consistency in cosmetic formulations, making it a reliable ingredient for skincare products.
The production of Tetrapeptide-17 involves a process known as solid-phase peptide synthesis (SPPS). In this method, amino acids are sequentially added to a growing peptide chain anchored to a solid resin. This allows for precise control over the peptide sequence and ensures high purity and yield. Once the desired peptide chain is assembled, it is cleaved from the resin and purified, resulting in the final product used in various skincare formulations.
Tetrapeptide-17 is also known by other names, such as N-Acetyl-Tetrapeptide-17, reflecting its chemical structure and the acetylation process it undergoes to enhance its stability and efficacy. This peptide has become a popular ingredient in anti-aging and skin-rejuvenating products, thanks to its ability to condition the skin and potentially improve its appearance.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Tetrapeptide-17:
Tetrapeptide-17 is primarily known for its skin conditioning properties. In simple terms, this means it helps to maintain the skin in good condition. When used in cosmetic formulations, Tetrapeptide-17 can contribute to making your skin feel softer, smoother, and more hydrated. It works by supporting the skin’s natural functions, helping to improve its overall appearance and texture. This can be particularly beneficial for those looking to enhance their skin’s suppleness and resilience.
Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Tetrapeptide-17 is generally considered safe for topical application in cosmetic products. It is designed to condition the skin and is typically well-tolerated by most individuals. However, as with any cosmetic ingredient, there are potential side effects that users should be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Tetrapeptide-17 during pregnancy and breastfeeding are lacking. Therefore, it is recommended that these individuals consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Tetrapeptide-17 are relatively uncommon. However, it is always prudent to conduct a patch test before widespread usage to ensure that the ingredient does not cause any adverse reactions on your skin.
In terms of comedogenicity, Tetrapeptide-17 is rated as a 0 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means that Tetrapeptide-17 is unlikely to clog pores and is generally safe for individuals who are prone to acne, blemishes, or breakouts.
