Article last updated: October 15, 2024
Sr-Egyptian Scorpion Oligopeptide-1, also known as Chlorotoxin, is a fascinating ingredient derived from an unexpected source: the venom of the Egyptian scorpion, Leiurus quinquestriatus. This single chain recombinant protein is produced through a sophisticated fermentation process in E. coli bacteria. The gene used to create this protein is synthesized to be identical to the natural gene found in the scorpion, ensuring that the resulting oligopeptide is a perfect match to its natural counterpart. The parent protein is composed of up to 36 amino acids, which may include disulfide bonds and glycosylation, and consists of the proper sequence of the 20 standard amino acids.
The journey of Sr-Egyptian Scorpion Oligopeptide-1 into the world of cosmetics is quite intriguing. Initially, Chlorotoxin was studied for its potential in medical applications, particularly in targeting cancer cells. However, researchers soon discovered its unique properties that could benefit the skin, leading to its adoption in the cosmetic industry. Its ability to condition the skin has made it a sought-after ingredient in various skincare formulations.
The production of Sr-Egyptian Scorpion Oligopeptide-1 involves a meticulous biotechnological process. Scientists start by inserting the synthesized gene into E. coli bacteria, which then act as tiny factories, producing the oligopeptide through fermentation. Once the fermentation process is complete, the protein is carefully extracted and purified to ensure it meets the high standards required for cosmetic use. This method not only ensures a consistent and high-quality product but also makes it possible to produce the ingredient on a larger scale, making it accessible for use in various skincare products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Sr-Egyptian Scorpion Oligopeptide-1:
Sr-Egyptian Scorpion Oligopeptide-1 is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition, making it feel smoother, softer, and more hydrated. By enhancing the skin’s overall texture and appearance, it can contribute to a healthier and more youthful look. This ingredient works by interacting with the skin’s natural processes, promoting better moisture retention and potentially aiding in the repair of minor skin damage.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Sr-Egyptian Scorpion Oligopeptide-1 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sr-Egyptian Scorpion Oligopeptide-1 during pregnancy and breastfeeding are lacking. Therefore, it is recommended that they consult a healthcare professional for further advice.
Side effects and adverse reactions from this ingredient are generally uncommon. However, it is advisable to conduct a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, Sr-Egyptian Scorpion Oligopeptide-1 is rated at 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This low rating means it is unlikely to clog pores and is generally suitable for people prone to acne, blemishes, or breakouts.
