Article last updated: October 15, 2024
Sh-Octapeptide-2, also known as sh-Oligopeptide-2, is a synthetic peptide designed to mimic a specific segment of the human protein Somatotropin. This peptide is composed of eight amino acids: aspartic acid, glutamic acid, glutamine, glycine, isoleucine, leucine, and lysine. In the realm of cosmetics, Sh-Octapeptide-2 is primarily recognized for its skin conditioning and skin protecting properties, as officially listed in the CosIng Database.
The journey of Sh-Octapeptide-2 into the world of cosmetics is rooted in the broader exploration of peptides for skincare. Initially studied for their potential in medical and therapeutic applications, peptides like Sh-Octapeptide-2 have found a niche in cosmetic formulations due to their ability to interact with skin cells and influence various biological processes. The use of peptides in skincare gained momentum in the early 2000s, driven by advancements in biotechnology and a growing understanding of skin biology.
Sh-Octapeptide-2 is produced through a synthetic process that involves the sequential addition of amino acids in a specific order to form the desired peptide chain. This method, known as solid-phase peptide synthesis (SPPS), allows for precise control over the peptide’s structure and purity. The resulting peptide is identical to the naturally occurring segment of Somatotropin, ensuring its compatibility and effectiveness when applied to the skin.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Sh-Octapeptide-2:
Sh-Octapeptide-2 is known for its skin conditioning properties. This means it helps to maintain the skin in good condition, making it feel softer, smoother, and more supple. When applied in cosmetic formulations, it can enhance the overall texture and appearance of the skin, giving it a more youthful and radiant look. Essentially, it acts as a moisturizer and conditioner, ensuring your skin stays hydrated and healthy.
Another significant benefit of Sh-Octapeptide-2 is its ability to protect the skin. This function involves shielding the skin from environmental stressors such as pollution, UV radiation, and other harmful elements. By forming a protective barrier, Sh-Octapeptide-2 helps to prevent damage and maintain the integrity of the skin. This protective quality is crucial for maintaining a youthful appearance and preventing premature aging.
Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Sh-Octapeptide-2 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sh-Octapeptide-2 during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Adverse reactions to Sh-Octapeptide-2 are relatively uncommon, but it is always prudent to perform a patch test before widespread usage to ensure there are no adverse reactions.
Sh-Octapeptide-2 has a comedogenic rating of 0, meaning it is considered non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
