Article last updated: October 15, 2024
Sh-Hexapeptide-3, also known as Sulfotransferase 2B1 (ST2B1), is a synthetic peptide commonly used in cosmetic formulations for its skin conditioning properties. This ingredient is part of a broader category of peptides, which are short chains of amino acids that serve as the building blocks of proteins. In the context of cosmetics, Sh-Hexapeptide-3 is prized for its ability to enhance the appearance and feel of the skin, making it a popular choice in anti-aging and skin-rejuvenating products.
The history of Sh-Hexapeptide-3 in cosmetics is relatively recent, emerging from advancements in peptide synthesis and biotechnology. Initially, peptides were studied for their roles in biological processes and medical applications. However, as research progressed, their potential benefits for skin health and appearance became evident. This led to the incorporation of peptides like Sh-Hexapeptide-3 into skincare products, where they are now celebrated for their ability to support skin structure and function.
Sh-Hexapeptide-3 is typically produced through a process known as solid-phase peptide synthesis (SPPS). This method involves sequentially adding amino acids to a growing peptide chain anchored to a solid resin. Each amino acid is protected by specific chemical groups to prevent unwanted reactions. Once the desired peptide sequence is complete, the peptide is cleaved from the resin and purified. This meticulous process ensures the production of high-purity Sh-Hexapeptide-3, suitable for use in cosmetic formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Sh-Hexapeptide-3:
Sh-Hexapeptide-3 is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition by improving its overall appearance and feel. When used in cosmetic formulations, Sh-Hexapeptide-3 can make your skin feel softer, smoother, and more hydrated. Essentially, it works to enhance the texture of your skin, making it look healthier and more vibrant.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Sh-Hexapeptide-3 is generally considered safe for topical application in cosmetic products. However, as with any skincare ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sh-Hexapeptide-3 during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Sh-Hexapeptide-3 are generally uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure that your skin does not react negatively to the ingredient.
In terms of comedogenicity, Sh-Hexapeptide-3 has a rating of 0, meaning it is considered non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
