Article last updated: October 15, 2024
Sh-Heptapeptide-2, also known as 18 kDa Phosphoprotein or p18, is a synthetic peptide composed of seven amino acids. In the realm of cosmetic ingredients, it is primarily recognized for its skin conditioning properties. This peptide is designed to mimic naturally occurring proteins in the skin, aiming to enhance the skin’s overall appearance and health.
The journey of Sh-Heptapeptide-2 into the world of cosmetics is rooted in the broader exploration of peptides for skincare. Peptides have long been studied for their potential to support skin structure and function. Sh-Heptapeptide-2 emerged from this research as a promising candidate due to its specific sequence and molecular weight, which allow it to interact effectively with skin cells.
The production of Sh-Heptapeptide-2 involves sophisticated biotechnological processes. Typically, it is synthesized through solid-phase peptide synthesis (SPPS), a method that allows for the precise assembly of amino acids into the desired sequence. This process ensures high purity and consistency, making it suitable for use in various cosmetic formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Sh-Heptapeptide-2:
Sh-Heptapeptide-2 is primarily recognized for its skin conditioning properties. This means that it helps to maintain the skin in good condition. When included in cosmetic formulations, Sh-Heptapeptide-2 can enhance the appearance and feel of the skin, making it softer, smoother, and more supple. This can be particularly beneficial for individuals with dry or rough skin, as it helps to restore moisture and improve texture.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Sh-Heptapeptide-2 is generally considered safe for topical application in cosmetic products. However, as with any skincare ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sh-Heptapeptide-2 during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Sh-Heptapeptide-2 are generally uncommon. However, it is recommended to conduct a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, Sh-Heptapeptide-2 is rated at 0 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means that Sh-Heptapeptide-2 is unlikely to clog pores and is generally suitable for individuals prone to acne, blemishes, or breakouts.
