Article last updated: October 15, 2024
Rh-Polypeptide-1, also known as Basic Fibroblast Growth Factor (bFGF) or FGF-2, is a single chain recombinant human peptide. This sophisticated ingredient is produced through a fermentation process in E. coli bacteria, starting from a gene directly isolated from human cells. The gene codes for the Basic Fibroblast Growth Factor, which is a protein that can contain up to 210 amino acids, potentially featuring disulfide bonds and glycosylation. Essentially, Rh-Polypeptide-1 is composed of the proper sequence of standard amino acids, making it a highly specialized and functional protein.
The journey of Rh-Polypeptide-1 into the world of cosmetics is quite fascinating. Initially, the Basic Fibroblast Growth Factor was studied for its role in wound healing and tissue repair due to its ability to stimulate cell growth and differentiation. Over time, researchers discovered its potential benefits for skin health, leading to its incorporation into various skincare products. The peptide’s ability to condition and protect the skin made it a valuable addition to anti-aging and rejuvenating formulations.
The production of Rh-Polypeptide-1 involves advanced biotechnological methods. The process begins with the isolation of the gene responsible for bFGF from human cells. This gene is then inserted into E. coli bacteria, which are cultured in a controlled environment to produce the peptide through fermentation. After fermentation, the peptide is extracted and purified to ensure its efficacy and safety for use in cosmetic products. This meticulous production process ensures that Rh-Polypeptide-1 retains its functional properties, making it a potent ingredient in skincare formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Rh-Polypeptide-1:
Rh-Polypeptide-1 is known for its skin conditioning properties. This means it helps to maintain the skin in good condition. When applied in cosmetic formulations, it can enhance the appearance of dry or damaged skin by reducing flaking and restoring suppleness. Essentially, it helps to keep your skin looking and feeling healthy, smooth, and hydrated.
Another significant benefit of Rh-Polypeptide-1 is its ability to protect the skin. This function involves shielding the skin from various environmental stressors, such as pollution and UV radiation, which can cause premature aging and damage. By incorporating Rh-Polypeptide-1 into skincare products, you can help fortify your skin’s natural barrier, making it more resilient against external aggressors.
Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Rh-Polypeptide-1 is generally considered safe for topical application, with a low allergenic potential. However, as with any cosmetic ingredient, there are potential side effects that users should be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Rh-Polypeptide-1 during pregnancy are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Rh-Polypeptide-1 are generally uncommon. However, it is recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
Rh-Polypeptide-1 has a comedogenicity rating of 1, meaning it is very unlikely to clog pores. This makes it a suitable option for individuals prone to acne, blemishes, or breakouts.
