Article last updated: October 15, 2024
R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) is a sophisticated and innovative ingredient in the world of cosmetics, known for its skin conditioning and skin protecting properties. This single chain recombinant peptide is produced through a fermentation process in E. coli, a common and well-studied bacterium. The creation of this peptide involves the fusion of genes from Tetrapeptide-69, Sh-Polypeptide-126, and Hexapeptide-40, resulting in a complex molecule that contains 355 amino acids. These amino acids are the building blocks of proteins and include the 20 standard amino acids found in the human body. The peptide may also feature disulfide bonds and glycosylation, which can influence its stability and function.
The journey of R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) into the realm of cosmetics is rooted in advancements in biotechnology and genetic engineering. Initially, peptides like this were studied for their potential in medical and pharmaceutical applications due to their ability to interact with biological systems in highly specific ways. Over time, researchers recognized the potential benefits of these peptides for skin care, leading to their incorporation into cosmetic formulations. The ability to produce these peptides through fermentation in E. coli has made it feasible to manufacture them at scale, ensuring consistent quality and availability for use in various products.
The production process of R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) begins with the synthesis of the starting gene, which is a carefully designed fusion of the genes from Tetrapeptide-69, Sh-Polypeptide-126, and Hexapeptide-40. This gene is then introduced into E. coli, where it directs the bacteria to produce the desired peptide. The fermentation process allows for the efficient production of the peptide, which is subsequently purified and prepared for inclusion in cosmetic products. This method ensures that the peptide is produced in a controlled environment, maintaining its integrity and effectiveness for skin care applications.
In this section, we will delve into the officially recognized cosmetic benefits and uses of R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40):
R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition. When applied in cosmetic formulations, it can enhance the appearance of dry or damaged skin by reducing flaking and restoring suppleness. Essentially, it acts as a moisturizer, making your skin feel softer and smoother. This is particularly beneficial for those with dry skin or those looking to maintain a youthful, hydrated appearance.
Another significant benefit of R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) is its skin protecting function. This ingredient helps to shield the skin from external aggressors such as pollutants and harsh environmental conditions. By forming a protective barrier on the skin’s surface, it can prevent damage from free radicals and other harmful elements. This protective quality is crucial for maintaining healthy skin and preventing premature aging caused by environmental stressors.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) is generally considered safe for topical use in cosmetic products. However, as with any skincare ingredient, it is important to be aware of potential side effects and considerations.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) during pregnancy and breastfeeding are lacking. It is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Adverse reactions to R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) are uncommon, but it is still recommended to conduct a patch test before widespread usage to ensure personal tolerance.
In terms of comedogenicity, R-(Tetrapeptide-69 Sh-Polypeptide-126 Hexapeptide-40) is rated as a 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means it has a low likelihood of clogging pores and causing acne or breakouts, making it suitable for individuals prone to blemishes.
