Article last updated: October 15, 2024
Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 is a fascinating fusion peptide that has been making waves in the cosmetic industry. This ingredient is derived from Nicotiana benthamiana, a plant that has been genetically transformed to produce a single chain recombinant human peptide. Essentially, scientists have inserted a human gene into the plant’s DNA, enabling it to produce a peptide identical to the human Insulin-Like Growth Factor 1 (IGF-1). The resulting fusion peptide contains 68 amino acids and may include disulfide bonds and glycosylation, ensuring it mimics the structure of human proteins closely.
The journey of Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 into the realm of cosmetics is quite intriguing. Initially, the technology behind this peptide was developed for medical and pharmaceutical applications, particularly in the production of therapeutic proteins. However, its potential for skin and hair conditioning soon caught the attention of cosmetic scientists. The ability to produce human-like peptides in plants offered a sustainable and scalable method to create high-quality cosmetic ingredients.
The production process involves either a transient expression system or transgenesis. In the transient expression system, the plant is temporarily transformed to produce the peptide, while transgenesis involves the stable insertion of the human gene into the plant’s DNA. The starting gene is synthesized to be identical to the human gene coding for IGF-1, which contains up to 195 amino acids. This sophisticated biotechnological approach ensures that the peptide produced is of high purity and efficacy, making it a valuable addition to cosmetic formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2:
Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 is known for its hair conditioning properties. This means it can help improve the texture and appearance of your hair. When included in hair care products, this ingredient works to make your hair feel softer, smoother, and more manageable. It can also help to reduce frizz and enhance shine, giving your hair a healthier and more vibrant look. Essentially, it acts as a nourishing agent that helps maintain the overall health and beauty of your hair.
Another significant benefit of Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 is its skin conditioning capability. This ingredient is designed to improve the feel and appearance of your skin. It works by providing hydration and nourishment, which can help to make your skin feel softer and more supple. Additionally, it can assist in maintaining the skin’s natural barrier, protecting it from environmental stressors and potential damage. By incorporating this ingredient into skincare products, you can achieve a more radiant and youthful complexion.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 during pregnancy are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice.
Adverse reactions to this ingredient are relatively uncommon, but it is always recommended to perform a patch test before widespread usage to ensure personal compatibility.
In terms of comedogenicity, Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 is rated as a 1 on a scale of 0 (totally non-comedogenic) to 5 (highly comedogenic). This means it is unlikely to clog pores and is generally suitable for individuals prone to acne, blemishes, or breakouts.
