Neohesperidin: An In-Depth Look at Its Role in Cosmetics

Article last updated: October 15, 2024

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Ever wondered what makes your skincare products so effective? Dive into the world of Neohesperidin and discover its transformative role in cosmetics, from its creation to its myriad benefits and potential side effects.

What Is Neohesperidin?

Neohesperidin is a naturally occurring flavonoid glycoside primarily found in citrus fruits, particularly in the bitter orange (Citrus aurantium). It is also known by its chemical name, (S)-7-[[2-O-6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one. This compound is part of a larger family of flavonoids, which are known for their antioxidant properties and various health benefits.

Historically, neohesperidin has been used in the food and beverage industry as a sweetening agent, particularly in the form of neohesperidin dihydrochalcone (NHDC), which is a derivative that is intensely sweet. Its journey into the cosmetic world began when researchers discovered its potential benefits for skin conditioning. This led to its inclusion in various skincare products aimed at improving skin texture and appearance.

The production of neohesperidin typically involves extracting it from citrus fruits through a series of processes that include solvent extraction, purification, and crystallization. The extracted compound is then refined to ensure its purity and efficacy for use in cosmetic formulations. This meticulous process ensures that the neohesperidin used in skincare products is of the highest quality, providing maximum benefits for the skin.

The Benefits/Uses of Neohesperidin

In this section, we will delve into the officially recognized cosmetic benefits and uses of Neohesperidin:

Skin Conditioning

Neohesperidin is primarily known for its skin conditioning properties. This means that it helps to maintain the skin in good condition. When used in cosmetic products, Neohesperidin can help to soften and smooth the skin, making it feel more supple and hydrated. This is particularly beneficial for individuals with dry or rough skin, as it can improve the overall texture and appearance of the skin.

Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

Neohesperidin is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind:

  • Skin irritation
  • Redness
  • Allergic reactions

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of neohesperidin during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.

Adverse reactions to neohesperidin are relatively uncommon, but it is always prudent to conduct a patch test before widespread usage to ensure there are no adverse reactions.

Neohesperidin has a comedogenic rating of 1, which means it is very unlikely to clog pores. This makes it a suitable option for individuals who are prone to acne, blemishes, or breakouts.

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