Article last updated: October 15, 2024
Tetrapeptide-46 is a synthetic peptide designed to mimic a segment of the scorpion protein known as Antimicrobial Peptide 143, which itself can contain up to 77 amino acids. This particular peptide is composed of just four amino acids: alanine, leucine, and phenylalanine. In the realm of cosmetics, Tetrapeptide-46 is primarily recognized for its skin conditioning properties, as listed in the CosIng Database.
The journey of Tetrapeptide-46 into the world of cosmetics is a fascinating one. Initially, peptides like this were studied for their antimicrobial properties, given their origin in scorpion venom. However, researchers soon discovered that certain peptides could offer significant benefits for skin health and appearance. This led to the development of Tetrapeptide-46, which was synthetically produced to ensure consistency and safety for cosmetic use.
The production of Tetrapeptide-46 involves sophisticated laboratory techniques where the specific sequence of amino acids is synthesized to create a peptide identical to the desired portion of the scorpion protein. This synthetic approach not only ensures a high degree of purity but also allows for large-scale production, making it feasible for inclusion in various skincare products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Tetrapeptide-46:
Tetrapeptide-46 is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition, keeping it soft, smooth, and healthy-looking. By mimicking a portion of the scorpion protein, Antimicrobial Peptide 143, Tetrapeptide-46 can assist in enhancing the skin’s overall appearance and texture. This makes it a valuable ingredient in various skincare products aimed at improving skin feel and appearance.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Tetrapeptide-46 is generally considered safe for topical application in cosmetic products. It is synthetically produced to mimic a portion of the scorpion protein, Antimicrobial Peptide 143, and is primarily used for its skin conditioning properties. However, as with any cosmetic ingredient, there are potential side effects and considerations to keep in mind.
– Skin irritation: Some individuals may experience mild irritation or redness upon application.
– Allergic reactions: Although rare, allergic reactions such as itching, swelling, or rash can occur.
– Sensitivity: People with sensitive skin may be more prone to experiencing adverse reactions.
Regarding individuals who are pregnant or breastfeeding, there is currently a lack of data and research on the topical usage of Tetrapeptide-46 during pregnancy and breastfeeding. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Adverse reactions to Tetrapeptide-46 are generally uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure that the ingredient does not cause any adverse reactions on your skin.
In terms of comedogenicity, Tetrapeptide-46 is rated as a 0 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means that Tetrapeptide-46 is unlikely to clog pores and is suitable for individuals who are prone to acne, blemishes, or breakouts.
