Article last updated: October 15, 2024
Tetrapeptide-38, also known as Dermican, is a synthetic peptide composed of four amino acids: glutamic acid, leucine, methionine, and tyrosine. In the realm of cosmetic science, peptides like Tetrapeptide-38 are highly valued for their skin-conditioning properties. This particular peptide is designed to enhance the skin’s overall appearance and texture, making it a popular ingredient in various skincare formulations.
The journey of Tetrapeptide-38 into the world of cosmetics is rooted in the broader exploration of peptides and their potential benefits for the skin. Initially studied for their roles in cellular communication and tissue repair, peptides have gradually found their way into skincare products due to their ability to promote skin health and vitality. Tetrapeptide-38 emerged from this research as a promising candidate for improving skin condition, leading to its incorporation in numerous beauty and skincare products.
The production of Tetrapeptide-38 involves sophisticated synthetic processes. Scientists use solid-phase peptide synthesis (SPPS) to create this peptide. In SPPS, amino acids are sequentially added to a growing peptide chain anchored to a solid resin. This method allows for precise control over the peptide’s sequence and structure, ensuring the final product is both effective and safe for use in cosmetics. Once synthesized, Tetrapeptide-38 undergoes rigorous testing to confirm its efficacy and stability before being included in skincare formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Tetrapeptide-38:
Tetrapeptide-38 is primarily known for its skin conditioning properties. This means that it helps to maintain the skin in good condition. In practical terms, this can translate to a variety of benefits such as improved skin texture, enhanced smoothness, and a more even skin tone. By conditioning the skin, Tetrapeptide-38 can help to make it feel softer and more supple, which is particularly beneficial for those with dry or rough skin.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Tetrapeptide-38 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects that users should be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Tetrapeptide-38 during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Tetrapeptide-38 are generally uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, Tetrapeptide-38 has a rating of 0, meaning it is considered non-comedogenic. This is particularly beneficial for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
