Article last updated: October 15, 2024
Tetrapeptide-37 is a synthetic peptide that has garnered attention in the cosmetic industry for its skin conditioning properties. Composed of four amino acids—arginine, aspartic acid, glycine, and serine—this peptide is designed to mimic natural peptides found in the skin.
The journey of Tetrapeptide-37 into the world of cosmetics is relatively recent, reflecting the broader trend of incorporating advanced biotechnological ingredients into skincare products. Initially developed through scientific research focused on understanding and replicating the skin’s natural processes, Tetrapeptide-37 was formulated to enhance skin health and appearance. Its introduction into cosmetic formulations represents a blend of cutting-edge science and the timeless quest for youthful, radiant skin.
The production of Tetrapeptide-37 involves sophisticated laboratory techniques. It is synthesized through a process known as solid-phase peptide synthesis (SPPS). In this method, amino acids are sequentially added to a growing peptide chain anchored to a solid resin. This allows for precise control over the peptide sequence, ensuring the creation of a highly pure and effective ingredient. Once the peptide chain is complete, it is cleaved from the resin and purified to remove any impurities, resulting in the final product used in skincare formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Tetrapeptide-37:
Tetrapeptide-37 is primarily known for its skin conditioning properties. This means that it helps to maintain the skin in good condition. When used in skincare products, Tetrapeptide-37 can improve the overall appearance and feel of the skin. It works by enhancing the skin’s natural barrier function, which helps to retain moisture and keep the skin hydrated. This can result in a smoother, softer, and more supple complexion. Additionally, well-conditioned skin is better equipped to protect itself from environmental stressors, which can contribute to a healthier and more resilient skin appearance.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Tetrapeptide-37 is generally considered safe for topical application in cosmetic products. It is suitable for most skin types and has a low allergenic potential. However, as with any cosmetic ingredient, there are potential side effects to be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Tetrapeptide-37 during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Tetrapeptide-37 are relatively uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
Tetrapeptide-37 has a comedogenicity rating of 0, meaning it is considered non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
