Article last updated: October 15, 2024
Sh-Tripeptide-3, also known as sh-Tripeptide-3, is a synthetic single chain human peptide that mirrors a segment of the protein Pro-Epidermal Growth Factor (Pro-EGF). This peptide is composed of three amino acids: cysteine, tyrosine, and valine. In the realm of cosmetic ingredients, it is primarily recognized for its skin conditioning properties.
The journey of sh-Tripeptide-3 into the world of cosmetics is rooted in the broader exploration of peptides and their potential benefits for skin health. Initially, peptides like sh-Tripeptide-3 were studied for their role in cellular communication and regeneration. As research progressed, scientists discovered that these small chains of amino acids could be synthesized to mimic natural proteins found in the skin, leading to their incorporation into skincare formulations.
The production of sh-Tripeptide-3 involves sophisticated synthetic processes. Scientists use techniques such as solid-phase peptide synthesis (SPPS) to create this peptide in the lab. This method allows for the precise assembly of amino acids in a specific sequence, ensuring that the resulting peptide is identical to the desired segment of Pro-EGF. The synthetic nature of sh-Tripeptide-3 ensures consistency and purity, making it a reliable ingredient for cosmetic applications.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Sh-Tripeptide-3:
Sh-Tripeptide-3 is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition. When included in cosmetic formulations, Sh-Tripeptide-3 can enhance the appearance and feel of the skin, making it softer, smoother, and more supple. This is particularly beneficial for those looking to improve the overall texture and hydration of their skin.
Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Sh-Tripeptide-3 is generally considered safe for topical application in cosmetic products. It is designed to be identical to a portion of the protein Pro-Epidermal Growth Factor and is primarily used for skin conditioning. However, as with any cosmetic ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sh-Tripeptide-3 during pregnancy and breastfeeding are lacking. Therefore, it is recommended that these individuals consult a healthcare professional for further advice before using products containing this ingredient.
Adverse reactions to Sh-Tripeptide-3 are generally uncommon, but it is always prudent to perform a patch test before widespread usage to ensure there is no sensitivity or allergic reaction to the ingredient.
Sh-Tripeptide-3 has a comedogenic rating of 0, meaning it is considered non-comedogenic. This is beneficial for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
