Article last updated: October 15, 2024
Sh-Tripeptide-1, also known as sh-oligopeptide-1, is a synthetic peptide designed to mimic a segment of the human protein Fibroblast Growth Factor 1 (FGF1). This peptide is composed of three amino acids: leucine, glutamic acid, and phenylalanine. In the realm of cosmetic ingredients, it is primarily recognized for its skin conditioning properties, as listed in the CosIng Database.
The journey of Sh-Tripeptide-1 into the world of cosmetics is rooted in the broader exploration of peptides and their potential benefits for skin health. Initially studied for their role in cellular communication and regeneration, peptides like Sh-Tripeptide-1 have garnered attention for their ability to support skin structure and function. The synthetic production of Sh-Tripeptide-1 ensures that it is identical to the naturally occurring segment of FGF1, allowing it to interact with the skin in a similar manner.
The manufacturing process of Sh-Tripeptide-1 involves sophisticated techniques in peptide synthesis. This typically includes the sequential addition of amino acids in a specific order to form the desired peptide chain. Advanced methods such as solid-phase peptide synthesis (SPPS) are often employed to ensure high purity and accuracy in the final product. This meticulous process guarantees that the synthetic peptide closely resembles its natural counterpart, making it a valuable addition to various skincare formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Sh-Tripeptide-1:
Sh-Tripeptide-1 is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition. When used in cosmetic formulations, it can enhance the appearance and feel of the skin, making it softer, smoother, and more supple. Essentially, it supports the skin’s overall health and vitality, contributing to a more youthful and refreshed look.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Sh-Tripeptide-1 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects that users should be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sh-Tripeptide-1 during pregnancy and breastfeeding are lacking. Therefore, it is recommended that these individuals consult a healthcare professional for further advice before using products containing this ingredient.
Adverse reactions to Sh-Tripeptide-1 are relatively uncommon, but it is always prudent to perform a patch test before widespread usage to ensure personal tolerance.
In terms of comedogenicity, Sh-Tripeptide-1 has a rating of 0, meaning it is considered non-comedogenic. This is particularly beneficial for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
