Article last updated: October 15, 2024
Sh-Polypeptide-77, also known as Glutaredoxin-1, is a synthetic peptide used primarily in cosmetic formulations for its skin conditioning properties. This ingredient is part of a larger family of polypeptides, which are essentially chains of amino acids linked together. In the context of skincare, Sh-Polypeptide-77 is designed to mimic natural proteins found in the skin, contributing to its overall health and appearance.
The history of Sh-Polypeptide-77 in cosmetics is relatively recent, emerging from advancements in biotechnology and peptide synthesis. Scientists discovered that certain peptides could offer significant benefits for skin health, leading to the development and incorporation of these compounds into various skincare products. The use of Sh-Polypeptide-77 specifically has gained traction due to its ability to support the skin’s natural functions and improve its condition.
The production of Sh-Polypeptide-77 involves sophisticated laboratory techniques. It is synthesized through a process known as solid-phase peptide synthesis (SPPS), where amino acids are sequentially added to a growing peptide chain anchored to a solid resin. This method allows for precise control over the peptide sequence, ensuring the creation of a highly pure and effective product. Once synthesized, the peptide is purified and tested for quality before being incorporated into cosmetic formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Sh-Polypeptide-77:
Sh-Polypeptide-77 is primarily known for its skin conditioning properties. This means that it helps to maintain the skin in good condition. In practical terms, this ingredient can help to keep your skin feeling soft, smooth, and hydrated. It works by forming a protective barrier on the skin’s surface, which helps to lock in moisture and prevent dryness. This can be particularly beneficial for individuals with dry or sensitive skin, as it can help to soothe and calm irritated areas.
Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Sh-Polypeptide-77, also known as Glutaredoxin-1, is generally considered safe for topical application in cosmetic products. However, as with any skincare ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sh-Polypeptide-77 during pregnancy are lacking. Therefore, it is advisable for pregnant or breastfeeding women to consult a healthcare professional for further advice before using products containing this ingredient.
Adverse reactions to Sh-Polypeptide-77 are relatively uncommon, but it is always prudent to perform a patch test before widespread usage to ensure you do not have a sensitivity to the ingredient.
Sh-Polypeptide-77 has a comedogenic rating of 0, meaning it is considered non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
