Article last updated: October 15, 2024
Silybin, also known as silibinin, is a naturally occurring flavonoid derived from the seeds of the milk thistle plant (Silybum marianum). Chemically, it is known as 3,5,7-Trihydroxy-2-(3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl)-4-chromanone. This complex name reflects its intricate molecular structure, which contributes to its potent biological activities.
The use of milk thistle extracts, including silybin, dates back centuries, primarily in traditional medicine for liver health. It wasn’t until more recent years that silybin’s potential benefits for skin care were explored and recognized. Researchers discovered that its antioxidant and anti-inflammatory properties could be harnessed to improve skin health, leading to its incorporation into various cosmetic formulations.
Silybin is typically extracted from milk thistle seeds through a process involving solvent extraction and purification. The seeds are first ground into a fine powder, which is then subjected to solvents like ethanol or methanol to dissolve the active compounds. The resulting solution is filtered and concentrated, followed by further purification steps to isolate silybin in its pure form. This purified silybin is then ready to be used as a skin-conditioning agent in cosmetic products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Silybin:
Silybin is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition. When used in cosmetic products, Silybin can improve the appearance and feel of the skin, making it softer, smoother, and more supple. It works by providing hydration and essential nutrients to the skin, which can help to enhance the skin’s natural barrier function. This is particularly beneficial for individuals with dry or sensitive skin, as it can help to alleviate dryness and irritation.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Silybin is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects to be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Silybin during pregnancy and breastfeeding are lacking. It is advisable for these individuals to consult a healthcare professional for further advice.
Adverse reactions to Silybin are relatively uncommon, but as with any new skincare ingredient, it is recommended to conduct a patch test before widespread usage to ensure there are no adverse reactions.
On the comedogenicity scale, Silybin is rated at 0, meaning it is considered non-comedogenic. This makes it suitable for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores.
