Article last updated: October 15, 2024
R-(Sh-Polypeptide-2 Decapeptide-40) is a single chain recombinant peptide that has found its way into the world of cosmetics, primarily for its skin conditioning and skin protecting properties. This ingredient is produced through a fermentation process in E. coli, a common bacterium used in biotechnology. The starting gene for this peptide is synthesized by fusing the genes encoding for sh-Polypeptide-2 and Decapeptide-40, resulting in a fusion peptide that contains 105 amino acids. These amino acids may form disulfide bonds and/or undergo glycosylation, and they consist of the 20 standard amino acids that are the building blocks of proteins.
The journey of R-(Sh-Polypeptide-2 Decapeptide-40) into cosmetic products is rooted in the advancements of biotechnology and genetic engineering. Initially, peptides like these were studied for their potential in medical applications, but their beneficial properties for skin health soon caught the attention of the cosmetic industry. The ability to produce these peptides in a controlled environment using E. coli fermentation has made it feasible to include them in skincare formulations.
The production process involves inserting the synthesized gene into E. coli, which then acts as a mini-factory to produce the peptide. After fermentation, the peptide is extracted and purified to ensure it meets the quality standards required for cosmetic use. This method not only ensures a high degree of purity but also allows for the production of peptides that are consistent in their composition and efficacy.
In this section, we will delve into the officially recognized cosmetic benefits and uses of R-(Sh-Polypeptide-2 Decapeptide-40):
R-(Sh-Polypeptide-2 Decapeptide-40) is known for its skin conditioning properties. This means it helps to maintain the skin in good condition. In practical terms, this ingredient can improve the overall appearance and feel of your skin. It can make your skin feel softer, smoother, and more hydrated. By enhancing the skin’s texture and suppleness, it contributes to a healthier and more youthful look.
Another significant benefit of R-(Sh-Polypeptide-2 Decapeptide-40) is its skin protecting function. This means it helps to shield the skin from various environmental stressors and potential damage. It can form a protective barrier on the skin’s surface, which helps to prevent the penetration of harmful substances and reduces the impact of external aggressors like pollution and UV radiation. This protective action helps to maintain the skin’s integrity and resilience, keeping it looking fresh and vibrant.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
R-(Sh-Polypeptide-2 Decapeptide-40) is generally considered safe for topical use in cosmetic products. However, as with any skincare ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of R-(Sh-Polypeptide-2 Decapeptide-40) during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from this ingredient are generally uncommon. However, as with any new skincare product, it is recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, R-(Sh-Polypeptide-2 Decapeptide-40) has a rating of 0 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means it is unlikely to clog pores and is generally suitable for people prone to acne, blemishes, or breakouts.
