Article last updated: October 15, 2024
Sh-Oligopeptide-103 Sp, also known as Dickkopf-1, Dkk-1, or hDkk-1, is a bioengineered peptide that has garnered attention in the cosmetic industry for its skin conditioning and skin protecting properties. This peptide is part of a larger family of proteins known as Dickkopf-related proteins, which play a crucial role in cellular signaling pathways, particularly those involved in skin health and regeneration.
The history of Sh-Oligopeptide-103 Sp in cosmetics is relatively recent, emerging from advanced biotechnological research aimed at harnessing the benefits of peptides for skin care. Initially studied for its role in inhibiting the Wnt signaling pathway, which is crucial for cell proliferation and differentiation, researchers discovered that this peptide could be beneficial for maintaining skin integrity and promoting a youthful appearance.
Sh-Oligopeptide-103 Sp is typically produced through recombinant DNA technology. This involves inserting the gene responsible for the peptide into a host organism, such as bacteria or yeast, which then produces the peptide through its natural biological processes. The peptide is subsequently purified and formulated into various cosmetic products. This method ensures a high degree of purity and consistency, making it a reliable ingredient for skin care formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Sh-Oligopeptide-103 Sp:
Sh-Oligopeptide-103 Sp is known for its skin conditioning properties. This means it helps to maintain the skin in good condition by improving its appearance and texture. When applied in cosmetic formulations, it can make your skin feel softer, smoother, and more hydrated. Essentially, it helps to keep your skin looking and feeling its best, which is a huge plus for anyone looking to enhance their skincare routine.
Another significant benefit of Sh-Oligopeptide-103 Sp is its skin protecting function. This ingredient helps to shield the skin from environmental stressors such as pollution, UV radiation, and harsh weather conditions. By forming a protective barrier on the skin’s surface, it can reduce the risk of damage and maintain the skin’s overall health. This protective quality is particularly beneficial for those living in urban areas or exposed to harsh environmental conditions.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Sh-Oligopeptide-103 Sp is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sh-Oligopeptide-103 Sp during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions to Sh-Oligopeptide-103 Sp are generally uncommon. However, it is recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, Sh-Oligopeptide-103 Sp is rated as a 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This low rating means it is unlikely to clog pores and is generally suitable for individuals prone to acne, blemishes, or breakouts.
