Article last updated: October 15, 2024
Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80, often referred to by its more manageable shorthand, is a synthetic fusion peptide that has been making waves in the cosmetic industry. This ingredient is a single chain synthetic fusion peptide produced through fermentation in E. coli. The creation process starts with the synthesis of a gene that fuses the individual genes from Tetrapeptide-38, Hexapeptide-40, Decapeptide-27, Oligopeptide-91, Dipeptide-19, and Sh-Polypeptide-80. The result is a peptide chain that contains 241 amino acids, composed of the proper sequence of the 20 standard amino acids.
The history of this peptide in cosmetics is relatively recent, driven by the ongoing quest for advanced skincare solutions. Scientists have been exploring the potential of peptides for their skin-conditioning and antioxidant properties, leading to the development of this complex fusion peptide. Its use in cosmetic products is a testament to the advancements in biotechnology and the increasing demand for effective skincare ingredients.
The production of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 involves a sophisticated biotechnological process. It begins with the synthesis of a custom gene that combines the genetic sequences of the individual peptides. This gene is then introduced into E. coli bacteria, which act as tiny bio-factories, producing the peptide through fermentation. Once the fermentation process is complete, the peptide is extracted and purified for use in cosmetic formulations. This method ensures a high degree of precision and consistency in the final product, making it a reliable ingredient for skincare applications.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80:
This ingredient functions as an antioxidant, which means it helps to neutralize free radicals that can cause damage to your skin. Free radicals are unstable molecules that can lead to premature aging, wrinkles, and other skin issues. By incorporating this peptide into your skincare routine, you can help protect your skin from environmental stressors like pollution and UV radiation, ultimately maintaining a healthier and more youthful appearance.
Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 also serves as a skin conditioning agent. This means it helps to improve the overall condition of your skin by enhancing its texture, smoothness, and hydration levels. Skin conditioning agents work by forming a protective barrier on the skin’s surface, which helps to retain moisture and keep the skin soft and supple. This can be particularly beneficial for those with dry or sensitive skin, as it helps to soothe and nourish the skin, making it look and feel healthier.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 is generally considered safe for topical application, with a low allergenic potential. However, as with any cosmetic ingredient, there are potential side effects that users should be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of this particular ingredient during pregnancy are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice.
Side effects and adverse reactions from this ingredient are relatively uncommon. However, it is recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
The comedogenicity of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 is rated at 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This low rating indicates that it is unlikely to clog pores, making it suitable for individuals prone to acne, blemishes, or breakouts.
